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Cellex solution for subcutaneous injection 0.1 mg /ml 1ml ampoule, 5 pcs.

Cellex solution for subcutaneous injection 0.1 mg /ml 1ml ampoule, 5 pcs.

$192.50

(In stock)

  • Cellex solution for subcutaneous injection 0.1 mg /ml 1ml ampoule, 5 pcs. - Cellex solution for subcutaneous injection 0.1 mg /ml 1ml ampoule, 5 pcs. -

Cellex solution for subcutaneous injection 0.1 mg /ml 1ml ampoule, 5 pcs.

Quick Overview

Cerebrovascular diseases: - acute disorders of cerebral circulation in the acute and early rehabilitation period of the course of the disease as part of complex therapy.

In Stock
$192.50

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Details

Dosage form

Transparent colorless or light yellow liquid, odorless or with a specific odor. Opalescence is allowed. The presence of inpidual threads of coagulate is allowed.

Compound

  • 1 ml
  • cellex® substance-solution (frozen, in terms of protein*) 0.1 mg
  • Excipients: glycine - 3.75 mg, sodium hydrogen phosphate dihydrate - 2.99 mg, sodium dihydrogen phosphate monohydrate - 0.47 mg, sodium chloride - 5.85 mg, water for injection - up to 1 ml.
  • * Composition per 1 ml.
  • Active substance: polypeptides from the brain of porcine embryos active substance in terms of total protein 0.9-2.4 mg (nominal total protein content 1.65 mg per 1 ml of substance).
  • Excipients: glycine - 3.75 mg, 0.1M disodium hydrogen phosphate solution - up to pH 7.8 (about 0.8 mg of dry matter), sodium chloride - 5.85 mg, polysorbate 80 - 0.005 mg, purified water - up to 1 ml.

Pharmacotherapeutic group

nootropic

Pharmacodynamics

The presence of tissue-specific signal proteins and polypeptides - growth factors, factors of differentiation of nerve cells in the preparation causes its direct neuroreparative effect, due to the regulation of the concentrations of the neurotransmitter pool, with inhibition of the spillover of excitatory amino acids.

The drug activates secondary neuroprotection by stimulating the processes of synaptogenesis, restoring autophagy signals, improving tissue immunoregulation with inhibition of the immunogenic cytotoxicity of macrophages. At the same time, it is noted

tissue-specific and systemic reparative action of the drug with the restoration of the regenerative and reparative potential of brain cells, a decrease in the number of damaged cells and the severity of perifocal edema in the penumbra zone (allows for a significant limitation of the focus of brain tissue necrosis) with the restoration of microcirculation and general perfusion.

Restoration and regulatory stimulation of various CNS compartments with systemic exposure to growth factors, differentiation, and signaling molecules reduces the recovery and rehabilitation of patients with damage to the central and peripheral nervous system of vascular origin and restoration of motor, sensory, and cognitive functions.

The therapeutic effect usually develops 3-5 days after the start of the drug administration.

Pharmacokinetics

The complex composition of the Cellex® preparation, the active fraction of which consists of a balanced and stable mixture of biologically active proteins and polypeptides with a total polyfunctional effect, does not allow for the usual pharmacokinetic analysis of inpidual components.

Indications

Cerebrovascular diseases:

- acute disorders of cerebral circulation in the acute and early rehabilitation period of the course of the disease as part of complex therapy.

Contraindications

- epilepsy;

- manic psychosis;

- productive nonsense;

- delirium;

- age up to 18 years (due to insufficient clinical data).

Use during pregnancy and lactation

The lack of relevant studies does not allow the use of the drug in this group of patients.

Use in children

The use of the drug in children and adolescents under the age of 18 is contraindicated.

Dosage and administration

For adults, the drug is prescribed at a dose of 0.1-0.2 mg 1 time / day s / c for 10 days, depending on the severity of the patient's condition. If necessary, repeat the course after 10 days. Studies on the use of the drug in pediatric practice have not been conducted.

Rules for the introduction of the solution

The drug is administered s / c through a sterile syringe filter included in the kit.

For administration, the required amount of Cellex® is taken into the syringe, the needle is removed, then a sterile sterile syringe filter with a pore diameter of 0.22 μm is put on the syringe. Take a new needle and put it on a sterile syringe filter. The drug is ready for use.

Side effects

Allergic reactions may occur in the form of unexpressed hyperemia at the injection site, hypersensitivity reactions (skin rash, itching, angioedema), low-grade fever, sleep disturbance, headache.

Overdose

Currently, there are no cases of overdose of Cellex®.

drug interaction

When used together with psychostimulant drugs and alcohol, psychomotor agitation, sleep disturbances are possible.

Perhaps a decrease in the activity of drugs for anesthesia, tranquilizers, antipsychotics.

Special conditions

With special care it is prescribed for arterial hypertension of a malignant course in the stage of decompensation; sympathetic-adrenal crises of the type of panic attacks; severe anxiety and depressive disorders.

During pregnancy, the effect of the drug has not been studied.

The drug does not contain prion infections and viruses.

Precautions for use

The drug should be prescribed with caution if there is a history of allergic reactions to drugs of a protein-peptide nature.

Influence on the ability to drive vehicles and control mechanisms

Currently, there is no data on the effect of Cellex® on the ability to drive a car and work with mechanisms that require increased attention and speed of mental and motor reactions.

Storage temperature

from 2 ℃ to 8 ℃

Additional Information

SKU rm-00010
Manufacturer PharmSintez
The purpose of the medication Cognitive Enhancement, Nootropic
Weight kg. 0.1

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